Collagen stimulators are a firming treatment involving the injection of a material that stimulates the production of type I and type III collagen, the two most important types. The treatment restores firmness, elasticity and radiance to the skin, with results that last for extended periods.
Collagen stimulators are a firming treatment involving the injection of a material that stimulates the production of type I and type III collagen, the two most important types. The treatment restores firmness, elasticity and radiance to the skin, with results that last for extended periods.
What does treatment with collagen stimulators involve?
The doctor assesses the patient and defines the lifting lines where the collagen-stimulating material will be injected. It is usually administered using a very fine cannula, with local anaesthetic injected beforehand at the entry points. The doctor’s technique and experience are extremely important.
Treatment with collagen stimulators takes approximately 30 minutes. An immediate tightening effect can be seen, followed by progressive improvement lasting from 12 months to 2 years, depending on the type of stimulating material used and the condition of the skin.
When are collagen stimulators recommended?
They are recommended for patients aged 30 and over who want to address the signs of ageing effectively without uncomfortable or invasive treatments, while achieving genuine, natural-looking results.
Collagen stimulators are indicated in the following cases:
- Firming the facial contour
- Lifting the outer brow
- Submalar augmentation
- Cheekbone augmentation and volumisation
- Cheeks
- Nasolabial folds
- Pre-jowl sulcus
- Marionette lines
- Chin augmentation
- Sagging buttocks and firming the skin on the abdomen, arms and knees
- Firming the facial contour
- Lifting the outer brow
- Submalar augmentation
- Cheekbone augmentation and volumisation
- Cheeks
- Nasolabial folds
- Pre-jowl sulcus
- Marionette lines
- Chin augmentation
- Sagging buttocks and firming the skin on the abdomen, arms and knees
Collagen stimulators before and after




Number of collagen stimulator sessions
- Normally, 1 session can achieve visible, long-lasting results.
- However, depending on the condition of the skin, up to 3 sessions may be recommended (1 session per month), particularly in cases of moderate skin laxity.
At Ribe Clinic in Barcelona, the medical specialist assesses each patient’s skin individually to determine the exact amount of product and the ideal treatment frequency for a natural, long-lasting tightening effect.
We also perform skin ultrasound scans with artificial intelligence assessment to measure the amount of collagen in the skin and its capacity to produce new collagen, allowing us to predict more accurately how many sessions the patient may need.

Aftercare following collagen stimulator injections
- Massage the treated area when applying cream during the first 24 hours; continuing for up to 5 days is recommended.
- If mild swelling or redness occurs, you can apply gentle local cooling or arnica cream.
- Do not use make-up or irritating cosmetics on the day of treatment.
- Keep the skin hydrated and protected with SPF 50 sunscreen.
Results of collagen stimulator treatment
The first collagen stimulator session produces an immediate tightening effect followed by progressive improvement lasting between 1 and 2 years, depending on the type of stimulator used and each person’s metabolism.
Frequently asked questions about collagen stimulators
Why Choose Ribe Clinic
Experience and Exclusivity
Dr Adriana Ribé personally conducts consultations and performs the medical treatments.
Medical Safety
Materials and devices with QR codes and CE certification. Scientifically supported protocols.
Patient Follow-up
Follow-up appointments and direct consultations with the doctor regarding the treatments performed.
Sustainable Clinic
The first aesthetic medicine clinic committed to sustainability.


