Can melasma be removed permanently?
Treating facial melasma is complex and requires long-term treatment, as it is a chronic pigmentation condition that cannot be permanently eliminated, although in many cases it can be significantly reduced.
I always tell my patients that a chronic condition requires ongoing treatment. Melasma treatment may involve a single therapy or a combination of treatments, including laser treatment (only certain lasers are approved), medical creams, oral medication and supplements, as well as sun protection.
Melasma before and after




Causes: why does melasma develop?
Melasma usually has a hormonal cause, whether due to pregnancy, hormonal treatments or even thyroid disorders or conditions affecting other endocrine organs. Once melasma appears on the face, it worsens in summer and with sun exposure at any time of year, even with indoor or outdoor light on cloudy days and with heat.
Melasma treatment at Ribe Clinic
The aim of melasma treatment is to lighten the pigmentation and reduce facial melasma as much as possible.
There are two approaches:
Creams
A thin layer of cream is applied to the face daily to reduce the continuous production of pigment (melanin) by melanocytes:
- Depigmenting creams
- Sun protection against UV rays, infrared radiation and blue light
Treatment of melasma with creams lasts for a minimum of 6 months.
Fraxel laser
The only laser approved by the FDA. We use the 1927 nm Fraxel laser once melanocyte pigment production is under control, whether with depigmenting creams, oral medication or supplements. In this way, one week after laser treatment, we aim to avoid a rebound effect with increased pigmentation.
Treatment involves 1 Fraxel laser session every 30 days (around 4 sessions)
Picosecond laser
A cold laser that is useful in the treatment of melasma because its thermal effect on melanocytes is minimal, helping to avoid a flare-up. More sessions are needed than with other lasers, but the treatments are gentler and are performed more frequently. We always aim to reduce melanocyte pigment production before laser treatment, whether with depigmenting creams, oral medication or supplements.
Treatment involves 1 picosecond laser session every 15–30 days (around 4–8 sessions).
Laser treatment for melasma is combined with exfoliating creams containing depigmenting ingredients, oral medication or supplements.
Frequently asked questions about melasma treatment with laser and creams
Why Choose Ribe Clinic
Experience and Exclusivity
Dr Adriana Ribé personally conducts consultations and performs the medical treatments.
Medical Safety
Materials and devices with QR codes and CE certification. Scientifically supported protocols.
Patient Follow-up
Follow-up appointments and direct consultations with the doctor regarding the treatments performed.
Sustainable Clinic
The first aesthetic medicine clinic committed to sustainability.



